BİYOLOJİK OLARAK SENTEZLENMİŞ GÜMÜŞ NANOPARTİKÜLLERİN SİTOTOKSİSİTESİ VE YARA İYİLEŞTİRME KAPASİTESİ

Metallic nanoparticles are interesting areas of research due to their unique properties which can be advantageous for producing smart products. Silver (AgNPs) remarkably used in pharmaceutical industry because strong biological activities. The aim the present study was investigate cytotoxicity and wound healing capacity biologically prepared silver via green synthesis route. Cytotoxicity biogenic AgNPs determined by MTT (3- [4, 5- dimethyl-2-thiazolyl]-2, 5-diphenyl-2H-tetrazolium-bromide) assay against L929 fibroblast cell line. Wound were evaluated using vitro-scratch 3T3 Biosynthesized inhibited propagation fibroblasts at a half maximal inhibitory concentration (IC50) 23.507 μg/mL after 24 h incubation. In vitro also revealed that stimulated fibroblasts' proliferation. It suggested synthesized effectively biomedical applications such as dressing materials.